How fast should I give propofol?

How fast should I give propofol?
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You're probably giving your propofol too quickly.

Long story short:

  • If you give it quickly, you generate a bigger concentration gradient, and there's a faster onset of action
  • If you give it slowly, you can avoid much of the haemodynamic compromise seen especially in higher risk and more frail patients

So there's clearly a speedy-stable-sleepy sweet spot to be found.

And I want to find it.