Conn's Syndrome in 30 seconds

@anaestheasier Conn's syndrome is a condition characterised by excess aldosterone. This causes a hypernatraemic, hypokalaemic, metabolic alkalosis #FRCA #novice #odp ♬ original sound - Anaestheasier

• Conn's syndrome is caused by an excess of aldosterone
• This has a wide array of targets in the body, but mainly acts on the kidney
• The first target is the sodium potassium ATPase pump, pumping three sodium ions into the blood, and two potassium ions in to the urine
• Note this makes the blood more electropositive than the urine, which the body isn't keen on, so negative chloride ions follow the sodium into the blood
• The second target is a hydrogen ion ATPase pump, which pumps H+ ions into the urine, producing the characteristic metabolic alkalosis

For our bigger article on Adrenal disease in anaesthesia, click here